BDBM499890 (S)-2-hydroxy-N-(cis-4-((5-(4- phenoxybenzoyl)-7H-pyrrolo[2,3- d]pyrimidin-4- yl)amino)cyclohexyl)propanamide::US11020398, Compound I-202

SMILES C[C@H](O)C(=O)N[C@H]1CC[C@H](CC1)Nc1ncnc2[nH]cc(C(=O)c3ccc(Oc4ccccc4)cc3)c12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499890   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Arqule

US Patent
LigandPNGBDBM499890((S)-2-hydroxy-N-(cis-4-((5-(4- phenoxybenzoyl)-7H-...)
Affinity DataIC50:  1nMAssay Description:The active BTK assay consisted of phosphorylated form of full length BTK. The assay was performed in a buffer solution utilized in the inactive BTK a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent