BDBM499901 (R)-N-((S)-1-((2S,5R)-5-((5-(2-chloro-4- phenoxybenzoyl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl)amino)tetrahydro-2H- pyran-2-yl)ethyl)-2- hydroxypropanamide::US11020398, Compound I-213
SMILES C[C@@H](O)C(=O)N[C@@H](C)[C@@H]1CC[C@H](CO1)Nc1ncnc2[nH]cc(C(=O)c3ccc(Oc4ccccc4)cc3Cl)c12
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 499901
Affinity DataIC50: 2.5nMAssay Description:The active BTK assay consisted of phosphorylated form of full length BTK. The assay was performed in a buffer solution utilized in the inactive BTK a...More data for this Ligand-Target Pair