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BDBM50000406 5-(2-Carboxy-ethyl)-pyridine-2-carboxylic acid::CHEMBL165469

SMILES: OC(=O)CCc1ccc(nc1)C(O)=O

InChI Key: InChIKey=OEUQNXWWSVIUTP-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000406   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF)


(Homo sapiens (Human))
BDBM50000406
PNG
(5-(2-Carboxy-ethyl)-pyridine-2-carboxylic acid | C...)
Show SMILES OC(=O)CCc1ccc(nc1)C(O)=O
Show InChI InChI=1S/C9H9NO4/c11-8(12)4-2-6-1-3-7(9(13)14)10-5-6/h1,3,5H,2,4H2,(H,11,12)(H,13,14)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.60E+3n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of prolyl 4-hydroxylase


J Med Chem 35: 800-4 (1992)


Article DOI: 10.1021/jm00083a001
BindingDB Entry DOI: 10.7270/Q25T3M3C
More data for this
Ligand-Target Pair