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BDBM50000524 6-Allyl-2-[2-(4-methoxy-phenyl)-ethyl]-3,3-dimethyl-2,3-dihydro-benzofuran-5-ol::CHEMBL25530

SMILES: COc1ccc(CCC2Oc3cc(CC=C)c(O)cc3C2(C)C)cc1

InChI Key: InChIKey=VOADRUOFYKAFQL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000524   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50000524
PNG
(6-Allyl-2-[2-(4-methoxy-phenyl)-ethyl]-3,3-dimethy...)
Show SMILES COc1ccc(CCC2Oc3cc(CC=C)c(O)cc3C2(C)C)cc1
Show InChI InChI=1S/C22H26O3/c1-5-6-16-13-20-18(14-19(16)23)22(2,3)21(25-20)12-9-15-7-10-17(24-4)11-8-15/h5,7-8,10-11,13-14,21,23H,1,6,9,12H2,2-4H3
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MMDB

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Similars

Article
PubMed
n/an/a 52n/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.


J Med Chem 35: 1299-318 (1992)


Article DOI: 10.1021/jm00085a019
BindingDB Entry DOI: 10.7270/Q25X27WS
More data for this
Ligand-Target Pair