BDBM50000714 3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one::3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one(WEB 2086)::3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-1-morpholin-4-yl-propan-1-one(WEB2086)::Apafant::CHEMBL280164::WEB2086
SMILES Cc1nnc2CN=C(c3cc(CCC(=O)N4CCOCC4)sc3-n12)c1ccccc1Cl
InChI Key InChIKey=JGPJQFOROWSRRS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50000714
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Rhone-Poulenc Sante
Curated by PDSP Ki Database
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Rhone-Poulenc Sante
Curated by PDSP Ki Database
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Affinity DataKi: 98nMAssay Description:In vitro intrinsic binding affinity at platelet activating factor receptor using rabbit platelet membranesMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of PAF-induced platelet aggregationMore data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Affinity DataIC50: 94nMAssay Description:Displacement of [3H]-PAF from PAF receptor of human platelet membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Affinity DataIC50: 200nMAssay Description:Inhibition of [3H]-PAF binding to dog platelets.More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Affinity DataIC50: 50nMAssay Description:Antagonistic activity for inhibition of [3H]PAF receptor binding to washed human platelet membranes.More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Affinity DataIC50: 200nMAssay Description:In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Affinity DataIC50: 40nMAssay Description:Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Rhone-Poulenc Sante
Curated by PDSP Ki Database
Affinity DataIC50: 200nMAssay Description:PAF-antagonist activity determined in dog platelets by PAF-binding assayMore data for this Ligand-Target Pair