BDBM50001110 8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-7,8-dihydro-3H-6,9-dioxa-3-aza-cyclopenta[a]naphthalene-2-carboxylic acid benzyl ester::CHEMBL318166
SMILES O=C(OCc1ccccc1)c1cc2c3OC(CN4CCC5(CC4)N(CNC5=O)c4ccccc4)COc3ccc2[nH]1
InChI Key InChIKey=DQQCWQGYIUCCKR-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50001110
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Binding affinity towards Dopamine receptor D2 from mammalian clones expressed in CHO cell membranes using 2 (86.1 Ci/mmol,1.7nanoM)as radioligandMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Upjohn
Curated by ChEMBL
Upjohn
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Upjohn
Curated by ChEMBL
Upjohn
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 143nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor expressed in CHO cell membranes using [3H]ketanserin (60 Ci/mmol, 1 nM)More data for this Ligand-Target Pair