BDBM50001214 3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL432091

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI Key InChIKey=NGCFKFBXSAWULW-CXDMSSIXSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001214   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001214(3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ET-1 binding to Endothelin A receptor in cultured rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B/1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001214(3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)
Affinity DataIC50:  5.80E+4nMAssay Description:Binding affinity against Endothelin receptor from rat heart ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001214(3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of ET-1 binding to Endothelin B receptor in cultured rat cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed