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BDBM50001562 5-(6-Imino-3-phenyl-6H-pyridazin-1-ylmethyl)-isoxazol-3-ol; hydrobromide::CHEMBL552953

SMILES: N=c1ccc(nn1Cc1cc(=O)[nH]o1)-c1ccccc1

InChI Key: InChIKey=YFZBHCKPWWLOER-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001562   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GABA receptor alpha-1 subunit


(Mus musculus)
BDBM50001562
PNG
(5-(6-Imino-3-phenyl-6H-pyridazin-1-ylmethyl)-isoxa...)
Show SMILES N=c1ccc(nn1Cc1cc(=O)[nH]o1)-c1ccccc1
Show InChI InChI=1S/C14H12N4O2/c15-13-7-6-12(10-4-2-1-3-5-10)16-18(13)9-11-8-14(19)17-20-11/h1-8,15H,9H2,(H,17,19)
PDB

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PC sid
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Similars

Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Centre de Neurochimie du CNRS

Curated by ChEMBL


Assay Description
Affinity for gamma-aminobutyric-acid A receptor measured by its ability to displace [3H]gabazine antagonist from rat brain preparations.


J Med Chem 35: 4092-7 (1992)


Article DOI: 10.1021/jm00100a015
BindingDB Entry DOI: 10.7270/Q25X29J4
More data for this
Ligand-Target Pair