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BDBM50001646 6-[4-(4-Isopropylamino-phenyl)-6-phenyl-pyridin-2-yloxy]-hexanoic acid::CHEMBL136955

SMILES: CC(C)Nc1ccc(cc1)-c1cc(OCCCCCC(O)=O)nc(c1)-c1ccccc1

InChI Key: InChIKey=MFBASASUQBXISA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001646   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50001646
PNG
(6-[4-(4-Isopropylamino-phenyl)-6-phenyl-pyridin-2-...)
Show SMILES CC(C)Nc1ccc(cc1)-c1cc(OCCCCCC(O)=O)nc(c1)-c1ccccc1
Show InChI InChI=1S/C26H30N2O3/c1-19(2)27-23-14-12-20(13-15-23)22-17-24(21-9-5-3-6-10-21)28-25(18-22)31-16-8-4-7-11-26(29)30/h3,5-6,9-10,12-15,17-19,27H,4,7-8,11,16H2,1-2H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 300n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair
LTB4R


(Homo sapiens (Human))
BDBM50001646
PNG
(6-[4-(4-Isopropylamino-phenyl)-6-phenyl-pyridin-2-...)
Show SMILES CC(C)Nc1ccc(cc1)-c1cc(OCCCCCC(O)=O)nc(c1)-c1ccccc1
Show InChI InChI=1S/C26H30N2O3/c1-19(2)27-23-14-12-20(13-15-23)22-17-24(21-9-5-3-6-10-21)28-25(18-22)31-16-8-4-7-11-26(29)30/h3,5-6,9-10,12-15,17-19,27H,4,7-8,11,16H2,1-2H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair