BDBM50001659 6-[6-Phenyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yloxy]-hexanoic acid::CHEMBL137303

SMILES OC(=O)CCCCCOc1cc(cc(n1)-c1ccccc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=XTXDJNFPMDIHOD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001659   

TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001659(6-[6-Phenyl-4-(4-trifluoromethyl-phenyl)-pyridin-2...)
Affinity DataIC50:  150nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001659(6-[6-Phenyl-4-(4-trifluoromethyl-phenyl)-pyridin-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001659(6-[6-Phenyl-4-(4-trifluoromethyl-phenyl)-pyridin-2...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed