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BDBM50001662 6-[4-(4-Nitro-phenyl)-6-phenyl-pyridin-2-yloxy]-hexanoic acid::CHEMBL137594

SMILES: OC(=O)CCCCCOc1cc(cc(n1)-c1ccccc1)-c1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=NSLGGKMLDOLNTH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001662   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene B4 receptor


(HUMAN)
BDBM50001662
PNG
(6-[4-(4-Nitro-phenyl)-6-phenyl-pyridin-2-yloxy]-he...)
Show SMILES OC(=O)CCCCCOc1cc(cc(n1)-c1ccccc1)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C23H22N2O5/c26-23(27)9-5-2-6-14-30-22-16-19(17-10-12-20(13-11-17)25(28)29)15-21(24-22)18-7-3-1-4-8-18/h1,3-4,7-8,10-13,15-16H,2,5-6,9,14H2,(H,26,27)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50001662
PNG
(6-[4-(4-Nitro-phenyl)-6-phenyl-pyridin-2-yloxy]-he...)
Show SMILES OC(=O)CCCCCOc1cc(cc(n1)-c1ccccc1)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C23H22N2O5/c26-23(27)9-5-2-6-14-30-22-16-19(17-10-12-20(13-11-17)25(28)29)15-21(24-22)18-7-3-1-4-8-18/h1,3-4,7-8,10-13,15-16H,2,5-6,9,14H2,(H,26,27)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 600n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair