BDBM50001664 6-[4-(4-Chloro-phenyl)-6-phenyl-pyridin-2-yloxy]-2-methyl-hexanoic acid::CHEMBL137494

SMILES CC(CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccc(Cl)cc1)C(O)=O

InChI Key InChIKey=LLXWFRMECZGHPV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001664   

TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001664(6-[4-(4-Chloro-phenyl)-6-phenyl-pyridin-2-yloxy]-2...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001664(6-[4-(4-Chloro-phenyl)-6-phenyl-pyridin-2-yloxy]-2...)
Affinity DataIC50:  40nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001664(6-[4-(4-Chloro-phenyl)-6-phenyl-pyridin-2-yloxy]-2...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed