BDBM50001677 22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-16-ol

SMILES Oc1ccc2CC3[C@@H]4Cc5c([nH]c6ccccc56)[C@@H]5Oc1c2[C@]45CCN3CCc1ccccc1

InChI Key InChIKey=ZEFONCRJOSMQGI-ADSSBNEFSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50001677   

TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001677(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataKi:  22nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001677(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataKi:  173nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001677(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataKi:  2.62E+3nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001677(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataIC50:  179nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed