BDBM50001795 1-(2-{4-[6-Chloro-1-(2-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL145706

SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3F)c3cc(Cl)ccc23)C1=O

InChI Key InChIKey=PHKYJSDVXODLTC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001795   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001795(1-(2-{4-[6-Chloro-1-(2-fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  300nMAssay Description:Displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001795(1-(2-{4-[6-Chloro-1-(2-fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  120nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001795(1-(2-{4-[6-Chloro-1-(2-fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed