BDBM50001809 3-(4-Fluoro-phenyl)-2,5-dimethyl-1-(1-methyl-piperidin-4-yl)-1H-indole::CHEMBL144362

SMILES CN1CCC(CC1)n1c(C)c(-c2ccc(F)cc2)c2cc(C)ccc12

InChI Key InChIKey=JHXVZNYMJMMPEI-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50001809   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50001809(3-(4-Fluoro-phenyl)-2,5-dimethyl-1-(1-methyl-piper...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]-Ketanserin from rat cortical membrane 5-HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50001809(3-(4-Fluoro-phenyl)-2,5-dimethyl-1-(1-methyl-piper...)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]-spiperone from rat striatal membrane D2 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50001809(3-(4-Fluoro-phenyl)-2,5-dimethyl-1-(1-methyl-piper...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [3H]prazosin from rat whole brain alpha1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50001809(3-(4-Fluoro-phenyl)-2,5-dimethyl-1-(1-methyl-piper...)
Affinity DataIC50:  2.60E+3nMAssay Description:Displacement of [3H]-spiperone from Dopamine receptor D2 rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50001809(3-(4-Fluoro-phenyl)-2,5-dimethyl-1-(1-methyl-piper...)
Affinity DataIC50:  2.70E+3nMAssay Description:Displacement of [3H]-prazosin from Alpha-1 adrenergic receptor in whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001809(3-(4-Fluoro-phenyl)-2,5-dimethyl-1-(1-methyl-piper...)
Affinity DataIC50:  5.30nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed