BDBM50001812 1-(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL144318

SMILES Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2ccc(F)cc12

InChI Key InChIKey=FKZJBKNKELKMSE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001812   

TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001812(1-(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indol-1-yl]-...)
Affinity DataIC50:  19nMAssay Description:Displacement of [3H]-prazosin from Alpha-1 adrenergic receptor in whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001812(1-(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indol-1-yl]-...)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001812(1-(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indol-1-yl]-...)
Affinity DataIC50:  250nMAssay Description:Displacement of [3H]-spiperone from Dopamine receptor D2 rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed