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BDBM50001960 5-(Benzyl-propyl-amino)-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL12285

SMILES: CCCN(Cc1ccccc1)C1Cc2cccc3[nH]c(=O)n(C1)c23

InChI Key: InChIKey=OOCMBXNFNITKHR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001960   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (human))
BDBM50001960
PNG
(5-(Benzyl-propyl-amino)-5,6-dihydro-1H,4H-imidazo[...)
Show SMILES CCCN(Cc1ccccc1)C1Cc2cccc3[nH]c(=O)n(C1)c23
Show InChI InChI=1S/C20H23N3O/c1-2-11-22(13-15-7-4-3-5-8-15)17-12-16-9-6-10-18-19(16)23(14-17)20(24)21-18/h3-10,17H,2,11-14H2,1H3,(H,21,24)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Ability to displace [3H]-DPAT from 5-hydroxytryptamine 1A receptor in homogenates of bovine hippocampus.


J Med Chem 35: 1076-92 (1992)


Article DOI: 10.1021/jm00084a013
BindingDB Entry DOI: 10.7270/Q2DB82GX
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50001960
PNG
(5-(Benzyl-propyl-amino)-5,6-dihydro-1H,4H-imidazo[...)
Show SMILES CCCN(Cc1ccccc1)C1Cc2cccc3[nH]c(=O)n(C1)c23
Show InChI InChI=1S/C20H23N3O/c1-2-11-22(13-15-7-4-3-5-8-15)17-12-16-9-6-10-18-19(16)23(14-17)20(24)21-18/h3-10,17H,2,11-14H2,1H3,(H,21,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.91E+3n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Ability to displace [3H]raclopride from dopamine receptor D2 in rat striatal homogenates.


J Med Chem 35: 1076-92 (1992)


Article DOI: 10.1021/jm00084a013
BindingDB Entry DOI: 10.7270/Q2DB82GX
More data for this
Ligand-Target Pair