BindingDB logo
myBDB logout

BDBM50001972 5-Dipropylamino-1-methyl-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL12515

SMILES: CCCN(CCC)C1Cc2cccc3n(C)c(=O)n(C1)c23

InChI Key: InChIKey=VKYJURCBISNWGU-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001972   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50001972
PNG
(5-Dipropylamino-1-methyl-5,6-dihydro-1H,4H-imidazo...)
Show SMILES CCCN(CCC)C1Cc2cccc3n(C)c(=O)n(C1)c23
Show InChI InChI=1S/C17H25N3O/c1-4-9-19(10-5-2)14-11-13-7-6-8-15-16(13)20(12-14)17(21)18(15)3/h6-8,14H,4-5,9-12H2,1-3H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
124n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to displace [3H]DPAT from 5-HT1A receptor in homogenates of bovine hippocampus


J Med Chem 35: 1076-92 (1992)


Article DOI: 10.1021/jm00084a013
BindingDB Entry DOI: 10.7270/Q2DB82GX
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50001972
PNG
(5-Dipropylamino-1-methyl-5,6-dihydro-1H,4H-imidazo...)
Show SMILES CCCN(CCC)C1Cc2cccc3n(C)c(=O)n(C1)c23
Show InChI InChI=1S/C17H25N3O/c1-4-9-19(10-5-2)14-11-13-7-6-8-15-16(13)20(12-14)17(21)18(15)3/h6-8,14H,4-5,9-12H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
924n/an/an/an/an/an/an/an/a



Upjohn Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to displace [3H]raclopride from dopamine receptor D2 in rat striatal homogenates


J Med Chem 35: 1076-92 (1992)


Article DOI: 10.1021/jm00084a013
BindingDB Entry DOI: 10.7270/Q2DB82GX
More data for this
Ligand-Target Pair