BDBM50002177 5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::5-methoxy-3-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)-1H-indole::CHEMBL130327

SMILES COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1

InChI Key InChIKey=OUSYTGMUXWLOBH-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50002177   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
E. Merck Darmstadt

Curated by ChEMBL
LigandPNGBDBM50002177(5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-...)
Affinity DataKi:  4.40nMAssay Description:Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonistMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
E. Merck Darmstadt

Curated by ChEMBL
LigandPNGBDBM50002177(5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-...)
Affinity DataIC50:  20nMAssay Description:Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes 3[H]spiperone, a dopamine antagonistMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50002177(5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
E. Merck Darmstadt

Curated by ChEMBL
LigandPNGBDBM50002177(5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50002177(5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed