BDBM50002334 1-(4-Fluoro-phenyl)-4-(4-pyrimidin-2-yl-piperazin-1-yl)-butan-1-one::4-[4-(2-Pyrimidine)piperazin-1-yl]-1-(4-fluorophenyl)-butan-1-one::CHEMBL140872
SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ncccn1
InChI Key InChIKey=WEVJMQOBCRCIPF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50002334
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.53nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]DOI from human 5HT2A receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 30.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 30.5nMAssay Description:Binding affinity to human cloned 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Displacement of [3H]clonidine from human Alpha-2C receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 244nMAssay Description:Binding affinity to human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 244nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 912nMAssay Description:Binding affinity to human cloned histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 912nMAssay Description:Displacement of [3H]pyrilamine from human H1 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.13E+3nMAssay Description:Binding affinity to human cloned 5HT2C receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Florida A&M University
Curated by ChEMBL
Florida A&M University
Curated by ChEMBL
Affinity DataKi: 4.13E+3nMAssay Description:Displacement of [3H]mesulergine from rat 5HT2C receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]WB-4101 binding to rat cortical Alpha-1 adrenergic receptor in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 679nMAssay Description:In vitro inhibitory against radioligand [3H]spiperone binding to rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Displacement of (+)-[3H]-3-PPP from rat cortical sigma siteMore data for this Ligand-Target Pair