BDBM50002347 CHEMBL425806::[N-cyclopropyl methylTyr1, D-pro10]Dynorphin A(1-11)

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NCC1CC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O

InChI Key InChIKey=CFPWTFGNSPUUJD-GZFUILBVSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50002347   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002347(CHEMBL425806 | [N-cyclopropyl methylTyr1, D-pro10]...)
Affinity DataKi:  0.0200nMAssay Description:Tested for inhibitory effect on binding of [3H]bremazocine to opioid receptor kappa in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002347(CHEMBL425806 | [N-cyclopropyl methylTyr1, D-pro10]...)
Affinity DataKi:  9.60nMAssay Description:Tested for inhibitory effect on binding of [3H]DAMGO to opioid receptor mu in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002347(CHEMBL425806 | [N-cyclopropyl methylTyr1, D-pro10]...)
Affinity DataKi:  558nMAssay Description:Tested for inhibitory effect on binding of [3H]DPDPE to opioid receptor delta in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002347(CHEMBL425806 | [N-cyclopropyl methylTyr1, D-pro10]...)
Affinity DataIC50:  2.20nMAssay Description:Tested for opioid receptor agonistic activity in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed