BDBM50002350 CHEMBL265387::[N-allylTyr1, D-pro10]Dynorphin A(1-11)

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NCC=C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O

InChI Key InChIKey=MKKPRLAUMQVIGT-BMLSPESSSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50002350   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002350(CHEMBL265387 | [N-allylTyr1, D-pro10]Dynorphin A(1...)
Affinity DataKi:  0.0490nMAssay Description:Tested for inhibitory effect on binding of [3H]bremazocine to opioid receptor kappa in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002350(CHEMBL265387 | [N-allylTyr1, D-pro10]Dynorphin A(1...)
Affinity DataKi:  11nMAssay Description:Tested for inhibitory effect on binding of [3H]DAMGO to opioid receptor mu in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002350(CHEMBL265387 | [N-allylTyr1, D-pro10]Dynorphin A(1...)
Affinity DataKi:  449nMAssay Description:Tested for inhibitory effect on binding of [3H]DPDPE to opioid receptor delta in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002350(CHEMBL265387 | [N-allylTyr1, D-pro10]Dynorphin A(1...)
Affinity DataIC50:  18nMAssay Description:Tested for inhibitory effect on binding of [3H]DAMGO to opioid receptor mu in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed