BDBM50002978 CHEMBL119893::{1-[1-[1-Cyclohexylmethyl-2-hydroxy-4-(pyridin-2-ylsulfanyl)-butylcarbamoyl]-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)NC(CC1CCCCC1)C(O)CCSc1ccccn1

InChI Key InChIKey=BEFLIBGMQADGKE-AYFAOMBPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002978   

TargetRenin(Homo sapiens (Human))
E. Merck Darmstadt

Curated by ChEMBL
LigandPNGBDBM50002978(CHEMBL119893 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  130nMpH: 5.5Assay Description:In vitro inhibitory activity against human plasma renin at pH 5.5 for suppression of angiotensin I formation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed