BDBM50003038 CHEMBL26427::Dimethyl-[2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethyl]-amine

SMILES CN(C)CCc1cn(C)c2ccc3OCCCc3c12

InChI Key InChIKey=IQIJKZDKEPJSMH-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50003038   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50003038(CHEMBL26427 | Dimethyl-[2-(3-methyl-3,7,8,9-tetrah...)
Affinity DataKi:  2.69E+3nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003038(CHEMBL26427 | Dimethyl-[2-(3-methyl-3,7,8,9-tetrah...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1C receptor in pig choroid plexus using [3H]-mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003038(CHEMBL26427 | Dimethyl-[2-(3-methyl-3,7,8,9-tetrah...)
Affinity DataIC50:  81nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [125I]DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003038(CHEMBL26427 | Dimethyl-[2-(3-methyl-3,7,8,9-tetrah...)
Affinity DataIC50:  1.00E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003038(CHEMBL26427 | Dimethyl-[2-(3-methyl-3,7,8,9-tetrah...)
Affinity DataIC50:  9.30E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]- serotonin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50003038(CHEMBL26427 | Dimethyl-[2-(3-methyl-3,7,8,9-tetrah...)
Affinity DataIC50:  5.40E+3nMAssay Description:Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed