BDBM50003127 CHEMBL122193::CHEMBL1626562::CHEMBL16659::choline salt of 5-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-3H-[1,3,4]thiadiazole-2-thione
SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1nnc(S)s1
InChI Key InChIKey=MYNMGQGXYYHMEX-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50003127
Affinity DataIC50: 2.00E+4nMAssay Description:IC50 value against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:IC50 value against Prostaglandin G/H synthase 1 of human platelet rich plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:IC50 value against Prostaglandin G/H synthase 2 of murine J774A.1 cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:The compound was tested for the inhibition of Prostaglandin G/H synthase in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase in intactbasophilic rat leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of 5-lipoxygenase measured by the reduction of leukotriene B4 (LTB4) in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against 5-LipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of 5-LO (unknown origin)More data for this Ligand-Target Pair