BDBM50003181 (diastereomer-1) (1-{6-Cyclohexylmethyl-7-hydroxy-4,8,14-trioxo-10-[(2,2,2-trichloro-ethoxycarbonylamino)-methyl]-1,9-dioxa-5-aza-cyclotetradec-3-ylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester::(diastereomer-2) (1-{6-Cyclohexylmethyl-7-hydroxy-4,8,14-trioxo-10-[(2,2,2-trichloro-ethoxycarbonylamino)-methyl]-1,9-dioxa-5-aza-cyclotetradec-3-ylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester::CHEMBL125014

SMILES CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)N[C@H]1COC(=O)CCCC(CNC(=O)OCC(Cl)(Cl)Cl)OC(=O)[C@H](O)[C@H](CC2CCCCC2)NC1=O

InChI Key InChIKey=XNAWXALRYUGAJB-PGYNUPFDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003181   

TargetRenin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003181((diastereomer-1) (1-{6-Cyclohexylmethyl-7-hydroxy-...)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003181((diastereomer-1) (1-{6-Cyclohexylmethyl-7-hydroxy-...)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed