BDBM50003818 6-[4,5-Bis-(2-chloro-phenyl)-1H-imidazol-2-ylsulfanylmethyl]-4-hydroxy-4-methyl-tetrahydro-pyran-2-one::CHEMBL337736

SMILES C[C@]1(O)CC(CSc2nc(c([nH]2)-c2ccccc2Cl)-c2ccccc2Cl)OC(=O)C1

InChI Key InChIKey=VEJIXILKOCDFDI-OGDGHAERSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003818   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003818(6-[4,5-Bis-(2-chloro-phenyl)-1H-imidazol-2-ylsulfa...)
Affinity DataIC50:  140nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed