BDBM50004065 (S)-3-[4-(6-Amino-hexyloxy)-phenyl]-2-(butane-1-sulfonylamino)-propionic acid::3-[4-(6-Amino-hexyloxy)-phenyl]-2-(butane-1-sulfonylamino)-propionic acid::CHEMBL86115

SMILES CCCCS(=O)(=O)N[C@@H](Cc1ccc(OCCCCCCN)cc1)C(O)=O

InChI Key InChIKey=XGOJDBSLSPIZAZ-SFHVURJKSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50004065   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004065((S)-3-[4-(6-Amino-hexyloxy)-phenyl]-2-(butane-1-su...)
Affinity DataIC50:  3.30E+5nMAssay Description:Inhibition of human umbilical vein endothelial cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004065((S)-3-[4-(6-Amino-hexyloxy)-phenyl]-2-(butane-1-su...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of human umbilical vein endothelial cell adhesion to vitronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004065((S)-3-[4-(6-Amino-hexyloxy)-phenyl]-2-(butane-1-su...)
Affinity DataIC50:  780nMAssay Description:Inhibition of HUVEC attachment to human fibronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004065((S)-3-[4-(6-Amino-hexyloxy)-phenyl]-2-(butane-1-su...)
Affinity DataIC50:  780nMAssay Description:Inhibition of platelet aggregation as the concentration necessary to inhibit the change in light .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004065((S)-3-[4-(6-Amino-hexyloxy)-phenyl]-2-(butane-1-su...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human umbilical vein endothelial cell adhesion to fibronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed