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BDBM50004264 2-(3-Hydroxy-2-oxo-azetidin-3-ylmethyl)-succinic acid::CHEMBL144869

SMILES: OC(=O)C[C@H](C[C@@]1(O)CNC1=O)C(O)=O

InChI Key: InChIKey=CKMFSDRJXOLMOV-SPGJFGJESA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004264   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP-citrate synthase


(Rattus norvegicus)
BDBM50004264
PNG
(2-(3-Hydroxy-2-oxo-azetidin-3-ylmethyl)-succinic a...)
Show SMILES OC(=O)C[C@H](C[C@@]1(O)CNC1=O)C(O)=O
Show InChI InChI=1S/C8H11NO6/c10-5(11)1-4(6(12)13)2-8(15)3-9-7(8)14/h4,15H,1-3H2,(H,9,14)(H,10,11)(H,12,13)/t4-,8-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>2.00E+7n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Ltd.

Curated by ChEMBL


Assay Description
Reversible binding Ki was measured by the inhibition of the carbon-carbon bond cleavage activity against rat ATP-Citrate Lyase


J Med Chem 35: 4875-84 (1992)


Article DOI: 10.1021/jm00104a014
BindingDB Entry DOI: 10.7270/Q2G73FBC
More data for this
Ligand-Target Pair