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BDBM50004275 2-Oxo-1,2-dihydro-quinoline-4-carboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::CHEMBL148398

SMILES: CN1C2CCC1CC(C2)OC(=O)c1cc(=O)[nH]c2ccccc12

InChI Key: InChIKey=XCTVBULSHAYUDI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004275   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004275
PNG
(2-Oxo-1,2-dihydro-quinoline-4-carboxylic acid 8-me...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)c1cc(=O)[nH]c2ccccc12
Show InChI InChI=1S/C18H20N2O3/c1-20-11-6-7-12(20)9-13(8-11)23-18(22)15-10-17(21)19-16-5-3-2-4-14(15)16/h2-5,10-13H,6-9H2,1H3,(H,19,21)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Similars

Article
PubMed
4.40n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair