BDBM50004410 CHEMBL439774::{1-[1-{1-Cyclohexylmethyl-2-hydroxy-3-[3-methyl-1-(2-morpholin-4-yl-ethylcarbamoyl)-butane-1-sulfinyl]-propylcarbamoyl}-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)CC(C(=O)NCCN1CCOCC1)S(=O)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=NBIRSMNKLQGFQM-NVWQRDAZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004410   

TargetRenin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004410(CHEMBL439774 | {1-[1-{1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  88nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed