BDBM50004589 8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-dione::CHEMBL102859

SMILES CCn1c2nc([nH]c2c(=O)n(CC)c1=O)C1CCCC1

InChI Key InChIKey=ALAWEPCLEBECQL-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50004589   

TargetAdenosine receptor A1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50004589(8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]DPCPX from human recombinant A1 receptor expressed in CHOA1 cell membranes incubated for 60 mins by radioligand binding competiti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50004589(8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]DPCPX from human recombinant A1 receptor expressed in CHOA1 cell membranes incubated for 60 mins by radioligand binding competiti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004589(8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  19nMAssay Description:Binding affinity against adenosine A1 receptor in guinea pig forebrain membranes using N6-[3H]cyclohexyladenosine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50004589(8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]DPCPX from human recombinant A2B receptor expressed in human HEK293 cell membranes incubated for 30 mins by radioligand binding c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50004589(8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]DPCPX from human recombinant A2B receptor expressed in human HEK293 cell membranes incubated for 30 mins by radioligand binding c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50004589(8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  157nMAssay Description:Displacement of [3H]ZM241385 from human recombinant A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by radioligand binding ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50004589(8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  157nMAssay Description:Displacement of [3H]ZM241385 from human recombinant A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by radioligand binding ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004589(8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  440nMAssay Description:Binding affinity against adenosine A2 receptor in rat striatal membranes using N-[3H]-ethyladenosin-5''-uronamide as radioligand in the presence of 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50004589(8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  1.72E+3nMAssay Description:Displacement of [3H]NECA from human A3 receptor expressed in human HeLa cell membranes incubated for 180 mins by radioligand binding competition assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50004589(8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  1.72E+3nMAssay Description:Displacement of [3H]NECA from human A3 receptor expressed in human HeLa cell membranes incubated for 180 mins by radioligand binding competition assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed