BDBM50004676 1-(4-Fluoro-phenyl)-2-imidazol-1-yl-1-(4-pyridin-4-yl-phenyl)-ethanol::CHEMBL321024

SMILES OC(Cn1ccnc1)(c1ccc(F)cc1)c1ccc(cc1)-c1ccncc1

InChI Key InChIKey=DZGMNXWTQWGZTK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004676   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50004676(1-(4-Fluoro-phenyl)-2-imidazol-1-yl-1-(4-pyridin-4...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase of RBL-1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50004676(1-(4-Fluoro-phenyl)-2-imidazol-1-yl-1-(4-pyridin-4...)
Affinity DataIC50: >7.50E+5nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50004676(1-(4-Fluoro-phenyl)-2-imidazol-1-yl-1-(4-pyridin-4...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity of the compound against phospholipase A2 of Croatalus adamanteusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed