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BDBM50004720 6-Methoxy-5-methyl-1-phenyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one::CHEMBL334046

SMILES: COc1nc2n(ncc2c(=O)n1C)-c1ccccc1

InChI Key: InChIKey=CSQQTFMSQCJHME-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004720   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50004720
PNG
(6-Methoxy-5-methyl-1-phenyl-1,5-dihydro-pyrazolo[3...)
Show SMILES COc1nc2n(ncc2c(=O)n1C)-c1ccccc1
Show InChI InChI=1S/C13H12N4O2/c1-16-12(18)10-8-14-17(9-6-4-3-5-7-9)11(10)15-13(16)19-2/h3-8H,1-2H3
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PC sid
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Similars

Article
PubMed
n/an/a 4.80E+3n/an/an/an/an/an/a



Marion Merrell Dow Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CHA binding to Adenosine A1 receptor in rat cerebral cortical membranes


J Med Chem 35: 3263-9 (1992)


Article DOI: 10.1021/jm00095a024
BindingDB Entry DOI: 10.7270/Q2QF8RTH
More data for this
Ligand-Target Pair