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BDBM50004807 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-isobutyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL334349

SMILES: CC(C)CN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O

InChI Key: InChIKey=ZQBJFINZRZWLFI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004807   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50004807
PNG
(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-isobutyl-1-p...)
Show SMILES CC(C)CN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O
Show InChI InChI=1S/C27H34FN3O2/c1-21(2)19-30-20-31(24-7-4-3-5-8-24)27(26(30)33)14-17-29(18-15-27)16-6-9-25(32)22-10-12-23(28)13-11-22/h3-5,7-8,10-13,21H,6,9,14-20H2,1-2H3
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PC cid
PC sid
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Similars

Article
PubMed
0.0390n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from dopamine receptor D2


J Med Chem 35: 423-30 (1992)


Article DOI: 10.1021/jm00081a002
BindingDB Entry DOI: 10.7270/Q2B85725
More data for this
Ligand-Target Pair