BDBM50004881 (RS) PPG::Amino-(4-phosphono-phenyl)-acetic acid::Amino-(4-phosphono-phenyl)-acetic acid(RS-PPG)::CHEMBL277475::PPG

SMILES NC(C(O)=O)c1ccc(cc1)P(O)(O)=O

InChI Key InChIKey=JRQRKFDFHAPMGQ-UHFFFAOYSA-N

Data  10 KI  13 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50004881   

TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataKi:  210nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataKi:  1.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataKi:  4.70E+3nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataKi:  5.20E+3nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataKi:  1.85E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 7 (mGluR-7).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataKi: >2.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataKi: >3.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataKi: >5.00E+5nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataKi: >5.00E+5nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50: >5.00E+5nMAssay Description:Metabotropic glutamate receptor 1 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50: >5.00E+5nMAssay Description:Metabotropic glutamate receptor 5 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50: >3.00E+5nMAssay Description:Metabotropic glutamate receptor 2 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50:  4.70E+3nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50:  5.20E+3nMAssay Description:Metabotropic glutamate receptor 4 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50:  4.70E+3nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50:  5.20E+3nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50:  4.80E+4nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50:  4.80E+4nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50: >2.00E+5nMAssay Description:Metabotropic glutamate receptor 3 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50:  3.20E+3nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50:  210nMAssay Description:Metabotropic glutamate receptor 8 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50:  1.85E+5nMAssay Description:Metabotropic glutamate receptor 7 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed