BDBM50005253 (+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylamine::1-(2,4,5-trimethoxyphenyl)propan-2-amine::1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylamine::1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylamine(2,4,5-TMA)::CHEMBL8389

SMILES COc1cc(OC)c(OC)cc1CC(C)N

InChI Key InChIKey=TVSIMAWGATVNGK-UHFFFAOYSA-N

Data  10 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50005253   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005253((+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylami...)
Affinity DataKi:  58nMAssay Description:Compound was evaluated for the binding affinity towards rat pancreatic Cholecystokinin type A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005253((+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylami...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]DOB from 5HT2A in Sprague-Dawley rat cortex membranes measured after 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005253((+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylami...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor sites by using [3H]-Ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005253((+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylami...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005253((+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylami...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat cortex membranes measured after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005253((+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylami...)
Affinity DataKi:  1.25E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]ketanserin as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005253((+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylami...)
Affinity DataKi:  1.25E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor of rat frontal cortex using [3H]ketanserin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005253((+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylami...)
Affinity DataKi:  1.65E+3nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005253((+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylami...)
Affinity DataKi:  2.67E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1C receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]mesulergine ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50005253((+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylami...)
Affinity DataKi:  4.64E+4nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50005253((+/-)1-Methyl-2-(2,4,5-trimethoxy-phenyl)-ethylami...)
Affinity DataKd:  155nMAssay Description:Affinity against 5-hydroxytryptamine 2B receptor in the isolated rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed