BDBM50005459 4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-butyric acid::CHEMBL9485::CR 1409

SMILES CCCCCN(CCCCC)C(=O)[C@@H](CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=IEKOTSCYBBDIJC-LJQANCHMSA-N

Data  4 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50005459   

TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataKi:  22nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Center For Bio-Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataKi:  49nMAssay Description:Inhibition of [3H]-L-364,718 binding to cholecystokinin type A receptor in rat pancreas membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataKi:  1.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin(GUINEA PIG)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataKi:  2.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Center For Bio-Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type B receptor of mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCholecystokinin receptor type A(RAT)
Center For Bio-Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataIC50:  50nMAssay Description:Displacement of [125I](BH)-CCK-8 to Cholecystokinin type A receptor in rat pancreatic aciniMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataIC50:  5.60E+3nMAssay Description:Displacement of [3H](N-methyl-N-leucine)-CCK-8 to Cholecystokinin type B receptor of guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCholecystokinin receptor type A(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataIC50:  66nMAssay Description:Compound was evaluated for the binding affinity against Cholecystokinin type A receptor in cortical cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataIC50:  66nMAssay Description:Inhibition of [125I]-Bolton-Hunter CCK-8 binding to cholecystokinin type A receptor in guinea pig pancreatic membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005459(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataIC50:  1.24E+4nMAssay Description:Compound was evaluated for the binding affinity against CCK A receptor in cortical cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed