BDBM50005591 CHEMBL141807::CHEMBL3234617

SMILES [#8]-c1ccc(cc1)-[#6](=[#7]/c1ccccc1Cl)\c1ccc(-[#8])cc1

InChI Key InChIKey=KCIOZMOTULBIRT-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50005591   

TargetEstrogen receptor(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005591(CHEMBL141807 | CHEMBL3234617)
Affinity DataEC50:  1nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HepG2 cells assessed as transcriptional activation after 24 hrs by ERE-luciferase rep...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005591(CHEMBL141807 | CHEMBL3234617)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed