BDBM50005677 CHEMBL23957::OXO-M::Trimethyl-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-ammonium; iodide
SMILES C[N+](C)(C)CC#CCN1CCCC1=O
InChI Key InChIKey=CANZROMYQDHYHR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50005677
TargetMuscarinic acetylcholine receptor M2(RAT)
Medical Research Division Of American Cyanamid
Curated by ChEMBL
Medical Research Division Of American Cyanamid
Curated by ChEMBL
Affinity DataKi: 0.780nMAssay Description:Binding affinity at [3H]QNB and GppNHp radiolabeled muscarinic M2 receptor in rat heart.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
TargetMuscarinic acetylcholine receptor M2(RAT)
Medical Research Division Of American Cyanamid
Curated by ChEMBL
Medical Research Division Of American Cyanamid
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Binding affinity at [3H]CD radiolabeled muscarinic M2 receptor in rat cortex.More data for this Ligand-Target Pair
Affinity DataKi: 107nMAssay Description:Binding affinity to human cloned muscarinic M2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(RAT)
Medical Research Division Of American Cyanamid
Curated by ChEMBL
Medical Research Division Of American Cyanamid
Curated by ChEMBL
TargetMuscarinic acetylcholine receptor M2(RAT)
Medical Research Division Of American Cyanamid
Curated by ChEMBL
Medical Research Division Of American Cyanamid
Curated by ChEMBL
Affinity DataKi: 910nMAssay Description:Binding affinity at [3H]QNB radiolabeled muscarinic M2 receptor in rat cortex.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Medical Research Division Of American Cyanamid
Curated by ChEMBL
Medical Research Division Of American Cyanamid
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Binding affinity at [3H]PZ radiolabeled muscarinic M1 receptor in rat cortex.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(RAT)
Medical Research Division Of American Cyanamid
Curated by ChEMBL
Medical Research Division Of American Cyanamid
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Binding affinity at [3H]QNB and GppNHp radiolabeled muscarinic M2 receptor in rat heart.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 2.04E+4nMAssay Description:Binding affinity to human cloned muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Compound was tested in vitro for its binding affinity to muscarinic acetylcholine receptor from rat cortical homogenates using [3H]QNB as radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Compound was tested in vitro for its binding affinity to muscarinic acetylcholine receptor from rat cortical homogenates using [3H]OXO-M as radioliga...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:In vitro ability to displace [3H]oxotremorine-M (OXO-M) from rat cerebral cortex Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:In vitro ability to displace [3H]quinuclidinyl benzilate (QNB) from rat cerebral cortex Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to Muscarinic acetylcholine receptor in rat cerebral cortexMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Wuerzburg
Curated by ChEMBL
University Of Wuerzburg
Curated by ChEMBL
Affinity DataEC50: 1.80E+3nMAssay Description:Activation of M3-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signalMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 7.40E+3nMAssay Description:Activation of M1-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signalMore data for this Ligand-Target Pair
Affinity DataEC50: 700nMAssay Description:Tested against Muscarinic acetylcholine receptor M1 expressed in A9 L cell lineMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
University Of Wuerzburg
Curated by ChEMBL
University Of Wuerzburg
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Activation of M5-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signalMore data for this Ligand-Target Pair