BDBM50005688 CHEMBL3085518::N*1*-[1-Benzyl-3-(2-tert-butylcarbamoyl-pyrrolidin-1-yl)-2-hydroxy-3-oxo-propyl]-2-[2-(naphthalen-1-yloxy)-acetylamino]-succinamide

SMILES CC(C)(C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)COc1cccc2ccccc12

InChI Key InChIKey=HTMNHRZEFBOZIL-QEETYVBOSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50005688   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50005688(CHEMBL3085518 | N*1*-[1-Benzyl-3-(2-tert-butylcarb...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity against HIV Protease enzyme.(by Dixon analysis)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50005688(CHEMBL3085518 | N*1*-[1-Benzyl-3-(2-tert-butylcarb...)
Affinity DataIC50:  0.580nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50005688(CHEMBL3085518 | N*1*-[1-Benzyl-3-(2-tert-butylcarb...)
Affinity DataIC50:  0.579nMAssay Description:Inhibitory potency against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed