BDBM50005701 CHEMBL337283::N*1*-[1-Benzyl-3-(2-tert-butylcarbamoyl-pyrrolidin-1-yl)-2-hydroxy-3-oxo-propyl]-2-[(quinoline-2-carbonyl)-amino]-succinamide
SMILES CC(C)(C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1
InChI Key InChIKey=JVBMLUUKYDVROE-OBXRUURASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50005701
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research
Curated by ChEMBL
Syntex Research
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity against HIV protease enzyme.(by Dixon analysis)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research
Curated by ChEMBL
Syntex Research
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme (by Dixon analysis)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research
Curated by ChEMBL
Syntex Research
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibitory potency against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataEC50: 145nMAssay Description:Antiviral activity of the compound against HTLV-1 RF infected MT-2 cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research
Curated by ChEMBL
Syntex Research
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Compound was evaluated for the inhibition of HIV proteaseMore data for this Ligand-Target Pair