BDBM50005795 2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-purin-6-one::CHEMBL285627::PD-119229-2
SMILES Nc1nc2c(nc(N)[nH]c2=O)n1Cc1cccs1
InChI Key InChIKey=HANOSGYMKMNFON-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50005795
Affinity DataKi: 20.7nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using 2-amino-6-mercapto-7-methyl purine ribonucleoside (MESG) as subst...More data for this Ligand-Target Pair
Affinity DataKi: 35.7nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
Affinity DataKi: 67nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
Affinity DataKi: 67nMAssay Description:Tested for its inhibitory activity against human erythrocytic purine nucleoside phosphorylaseMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
Affinity DataIC50: 69.4nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair