BDBM50005811 CHEMBL285049::[1-(1-Hydroxymethyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-carbamic acid adamantan-2-yl ester;0.5H2O

SMILES OCC(Cc1ccccc1)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2

InChI Key InChIKey=KZAXYDRLQGEYNI-ZEWZGCCISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50005811   

TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50005811(CHEMBL285049 | [1-(1-Hydroxymethyl-2-phenyl-ethylc...)
Affinity DataIC50:  780nMAssay Description:Evaluated for in vitro binding affinity to cholecystokinin-A (CCK-A) receptor in homogenized rat pancreas using [125I]-Bolton hunter CCK26-33 as radi...More data for this Ligand-Target Pair
In DepthDetails Article
TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50005811(CHEMBL285049 | [1-(1-Hydroxymethyl-2-phenyl-ethylc...)
Affinity DataIC50:  852nMAssay Description:Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Parke-Davis Neuroscience Research Center

Curated by ChEMBL
LigandPNGBDBM50005811(CHEMBL285049 | [1-(1-Hydroxymethyl-2-phenyl-ethylc...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Parke-Davis Neuroscience Research Center

Curated by ChEMBL
LigandPNGBDBM50005811(CHEMBL285049 | [1-(1-Hydroxymethyl-2-phenyl-ethylc...)
Affinity DataIC50:  6.30nMAssay Description:Evaluated for in vitro binding affinity towards cholecystokinin-B (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton hunter CCK26-33 as ra...More data for this Ligand-Target Pair
In DepthDetails Article