BDBM50006132 CHEMBL297929::[1-[1-(1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-3-methyl-butylcarbamoyl]-2-(4-iodo-phenyl)-ethyl]-carbamic acid ethyl ester
SMILES CCOC(=O)N[C@@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CC(C)C
InChI Key InChIKey=TYLAYGSYBANABY-MYHRABSESA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50006132
Affinity DataIC50: 2.40nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
Affinity DataIC50: 300nMpH: 7.4Assay Description:In vitro potency against human plasma renin at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibitory activity was tested against purified human renal reninMore data for this Ligand-Target Pair