BDBM50006141 2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-oxo-ethoxy]-pentanoic acid (1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl)-amide::CHEMBL295687

SMILES CCC[C@H](O[C@@H](Cc1ccccc1)C(=O)N1CCC(CC1)OCOC)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CC(C)C

InChI Key InChIKey=RNEYLZROBLYYGT-PMUGGPHNSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50006141   

TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006141(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  3.30nMpH: 6.0Assay Description:In vitro potency against plasma renin at a pH of 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006141(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  31nMpH: 7.4Assay Description:In vitro potency against purified renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006141(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  1.40nMpH: 6.0Assay Description:In vitro potency against plasma renin at a pH of 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006141(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  5.5nMpH: 7.4Assay Description:In vitro potency against purified renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed