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BDBM50006468 (1-Benzooxazol-2-ylmethyl-5-chloro-1H-indazol-3-yl)-acetic acid::CHEMBL69907

SMILES: OC(=O)Cc1nn(Cc2nc3ccccc3o2)c2ccc(Cl)cc12

InChI Key: InChIKey=QGRXSXAZBNZZLT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006468   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase (AR)


(Homo sapiens (Human))
BDBM50006468
PNG
((1-Benzooxazol-2-ylmethyl-5-chloro-1H-indazol-3-yl...)
Show SMILES OC(=O)Cc1nn(Cc2nc3ccccc3o2)c2ccc(Cl)cc12
Show InChI InChI=1S/C17H12ClN3O3/c18-10-5-6-14-11(7-10)13(8-17(22)23)20-21(14)9-16-19-12-3-1-2-4-15(12)24-16/h1-7H,8-9H2,(H,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase isolated from human placenta


J Med Chem 35: 2155-62 (1992)


Article DOI: 10.1021/jm00090a002
BindingDB Entry DOI: 10.7270/Q2KK99RR
More data for this
Ligand-Target Pair