BDBM50006474 CHEMBL309132::[5-Oxo-6-(5-trifluoromethyl-benzothiazol-2-ylmethyl)-5,6-dihydro-pyrido[2,3-d]pyridazin-8-yl]-acetic acid

SMILES OC(=O)Cc1nn(Cc2nc3cc(ccc3s2)C(F)(F)F)c(=O)c2cccnc12

InChI Key InChIKey=WOEUAFRESFKHDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006474   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006474(CHEMBL309132 | [5-Oxo-6-(5-trifluoromethyl-benzoth...)
Affinity DataIC50:  41nMAssay Description:Inhibitory activity against aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed