BDBM50006776 3-Benzoyloxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 3-phenyl-propyl ester::CHEMBL84244

SMILES CN1[C@@H]2CCC1[C@H]([C@H](C2)OC(=O)c1ccccc1)C(=O)OCCCc1ccccc1

InChI Key InChIKey=LLAHJYBITWOMNU-FJPMACBPSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50006776   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006776(3-Benzoyloxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2...)
Affinity DataIC50:  139nMAssay Description:Inhibition of [3H]WIN-35248 binding to the dopamine transporter in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006776(3-Benzoyloxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2...)
Affinity DataIC50:  2.51E+4nMAssay Description:Compound was evaluated for the inhibition of [3H]mazindol binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006776(3-Benzoyloxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2...)
Affinity DataIC50:  139nMAssay Description:Compound was evaluated for the inhibition of [3H]WIN-35428l binding to dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006776(3-Benzoyloxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2...)
Affinity DataIC50:  374nMAssay Description:Inhibition of [3H]paroxetine binding to Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed