BDBM50007040 2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl]-thiazole::CHEMBL20953
SMILES COC1(CCc2ccc(OCc3ccc4ccccc4c3)cc12)c1nccs1
InChI Key InChIKey=PHWUGPWQJTXVQO-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50007040
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-LPO) in rat basophilic leukemia (RBL) cells.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: <30nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibitory concentration of the compound against 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-LPO) in rat basophilic leukemia (RBL) cells.More data for this Ligand-Target Pair